Climate change is affecting grape yields, wine composition, and quality. As a result, the geography of wine production is changing. In this review, we discuss the implications of changing temperature, precipitation, humidity, radiation, and CO ₂ on global wine production and explore adaptation strategies. Current wine-growing regions are primarily located in mid-latitudes (California, USA; southern France; northern Spain and Italy; Barossa, Australia; Stellenbosch, South Africa; and Mendoza, Argentina, among others), where the climate is warm enough to allow grapes to ripen, but not too hot and relatively dry to prevent severe disease pressure.  (Cornelis van Leeuwen, Giovanni Sgubin, Gregory A. Gambetta, more at nature.com)