Mining activities significantly contribute to the loss of forest cover (FCL), consequently to changing global carbon dynamics and worsening climate change. This study aims to estimate the contribution of mining-induced FCL to carbon sequestration loss (CSL) and carbon dioxide (CO₂) emissions from 2000 to 2019 using proxy datasets. For the FCL analysis, global FCL data with a spatial resolution of 30 m were developed by Hansen et al. (2013), was employed in the Google Earth Engine (GEE) cloud platform. In addition, Moderate Resolution Imaging Spectroradiometer (MODIS)-based Net Primary Productivity (NPP) data and biomass datasets developed by Zhang and Liang (2020) were used to assess CSL and CO₂ emissions. The results of the study showed approximately 16,785.90 km worldwide ² FCL due to mining activities, resulting in an estimated CSL of ∼36,363.17 Gg CO₂/yr and CO₂ emissions of ∼490,525.30 Gg CO₂. Indonesia emerged as the largest contributor to mining-induced FCL, accounting for 3,622.78 km ² of deforestation or 21.58 % of the global total. Brazil and Canada followed with significant deforestation and CO₂ emissions. The findings revealed that mining activities are a major driver of deforestation, especially in resource-rich regions, leading to substantial environmental degradation. (Avinash Kumar Ranjan, Amit Kumar Gorai, more at sciencedirect.com)